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More knowledge about nephrotic syndrome

New PhD thesis from DCE investigates the incidence of nephrotic syndrome (NS), the 1-year mortality risk as well as the long-term risks of having a thromboembolic event or bleeding after NS diagnosis.

Søren Viborg Vestergaard, who defended his PhD thesis today, has conducted three cohort studies on nephrotic syndrome (NS), which is a rare renal condition characterized by severe proteinuria and hypoalbuminemia in patients with primary glomerular diseases (primary NS) or systemic conditions (secondary NS).

He found that during 2004-2018, 18% of patients with nephrotic proteinuria and hypoalbuminemia had a diagnosis compatible with NS recorded at hospital within 1 year, while 87% had diagnoses reflecting any kind of nephropathy.

Søren and colleagues explored the incidence of hospital-recorded NS in adults, including changes in the incidence, mortality, and biopsy findings over the past 40 years. Lastly, they investigated the 10-year risk of experiencing a thromboembolic or bleeding event in adults with NS. These results are awaiting publication in scientific journals, and thus, cannot be presented here.