Aarhus University Seal

New guideline to strengthen research on social differences in health

A new cross-institutional initiative, SEPLINE, aims to support researchers working with social inequality in health by providing a shared foundation for how social differences are measured and analyzed. The national and interdisciplinary network has just published a consensus guideline designed to improve the consistency and quality of research in this field.

35 researchers across Danish universities and public institutions have developed the SEPLINE consensus guideline.
Postdoc Maja Halgren Olsen, the Danish Cancer Institute (Photo by Eilertsen).
Postdoc Cathrine F. Hjorth, Department of Clinical Epidemiology, Aarhus University (AU Photography).

SEPLINE was founded by Maja Halgren Olsen, postdoc at the Danish Cancer Institute, and Cathrine F. Hjorth, postdoc at Department of Clinical Epidemiology, Aarhus University. The idea arose from their shared experience of the challenges posed by inconsistent approaches to measuring socioeconomic differences across research institutions.

They observed that large variations in how socioeconomic position is defined and analyzed can lead to misinterpretations and hinder efforts to address health differences. Additionally, researchers often spend a significant amount of time navigating complex data sources. SEPLINE seeks to make this work more accessible and coherent. The national and interdisciplinary network was established in 2023 with support from the Danish Comprehensive Cancer Center.

Through two workshops in 2024 and an ongoing collaboration with researchers across Danish universities and public institutions, SEPLINE has developed a consensus guideline that offers practical recommendations on how to measure socioeconomic position and analyze social differences in health outcomes. It also highlights common pitfalls and limitations in commonly used data sources.

By fostering shared practices and better methodological understanding, SEPLINE hopes to strengthen the foundation for valid and comparable research across institutions. The guideline is intended to be a helpful resource for researchers designing studies on prevention, treatment, and rehabilitation – across all areas of health.

The initiative will also contribute to education and capacity building, including a new PhD course at Aarhus University scheduled in the fall of 2025.
   

SEPLINE

SEPLINE is a contraction of the guideline's title Socioeconomic position in epidemiological research – a national guideline on Danish registry data, which has just been published in the journal Clinical Epidemiology. Read it here